High Grade Glioma after Prophylactic Cranial Irradiation for Small Cell Lung Cancer
نویسندگان
چکیده
We report a patient with an initial diagnosis of small cell lung cancer treated with prophylactic cranial irradiation (PCI), who subsequently developed a second primary brain neoplasm within the PCI volume. Pathology review was consistent with astrocytoma, WHO grade IV (Glioblastoma Multiforme). After describing our case, we review the literature on the development of a second brain primary after treatment with PCI and discuss potential etiologies.
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