Pathological Spectrum of Cns Tumours: Five Year Study in a Tertiary Care Hospital
نویسندگان
چکیده
BACKGROUND: Tumours form an integral part of disease process affecting the CNS and constitute a major part of all intracranial space occupying lesions. AIM: To study the histological findings of CNS tumors and to classify them according to WHO classification. MATERIALS AND METHODS: This is a five year study in which all the specimens of tumors of brain and spinal cord received in the department of Pathology were analyzed with reference to histological type and grade of tumors by examination of hematoxylin and eosin stained slides and from information in pathology reports. RESULTS: A total of 315 cases were analyzed in the present study. Brain tumors formed the major part with a percentage of 87.9%, and tumors of spinal cord constituted 12.1% of all CNS tumors. All the brain and spinal cord tumors showed male preponderance except meningiomas in which male to female ratio was 1:2.3. Mean age of presentation of CNS tumors was 45.5 years. Overall, astrocytomas were the most common CNS tumors followed by meningiomas. Among the astrocytic tumors, glioblastoma multiforme was commonest accounting for 69.5% of all astrocytic tumors. Transitional meningioma was the most commonly observed meningeal tumor in brain as well as spinal cord. Pilocytic astrocytoma and medulloblastoma were the commonest tumors seen in childhood.
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