Single administration of intra - articular bupivacaine in arthroscopic 1 knee surgery : a systematic review and meta - analysis 2 3
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Single administration of intra-articular bupivacaine in arthroscopic knee surgery: a systematic review and meta-analysis
BACKGROUND Single administration of intra-articular (IA) bupivacaine for pain relief after arthroscopic knee surgery is effective, but its active duration and dose-response relationship is unclear. We conducted this meta-analysis to summarize all published randomized controlled trials (RCTs), thus providing the most recent information on the safety and efficacy of single-administration IA bupiv...
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Background: Arthroscopic intervention is very common for conducting orthopedic surgeries. After a knee arthroscopic surgery, different drugs are used through intra-articular administration to induce analgesia. The aim of this study was to evaluate analgesic effects of Bupivacaine (marcaine), Bupivacaine plus midazolam, and Bupivacaine plus fentanyl in reducing pain after knee arthroscopic sur...
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OBJECTIVES To evaluate the efficacy and safety of single-dose intra-articular bupivacaine plus morphine after knee arthroscopic surgery. DESIGN Meta-analysis. DATA SOURCES AND STUDY ELIGIBILITY CRITERIA A comprehensive literature search, using Medline (1966-2014), the Cochrane Central Register of Controlled Trials and Embase databases, was conducted to identify randomised placebo-controlled...
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OBJECTIVES The purpose of this study was to compare the efficacy and safety of a single-dose intra-articular morphine plus bupivacaine versus morphine alone in patients undergoing arthroscopic knee surgery. METHODS Randomized controlled trials comparing a combination of morphine and bupivacaine with morphine alone injected intra-articularly in the management of pain after knee arthrocopic sur...
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Background: Of the pharmacological modalities for knee osteoarthritis (OA), intra-articular injections including ozone(O3) and hyaluronic acid (HA) are commonly used for reducing pain and improving function. In this systematic reviewand meta-analysis, we aimed to compare the effect of O3 versus HA in reducing pain and increasing function in patientswith knee OA.Methods: ...
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