Endomysial antibody in the diagnosis and management of coeliac disease.
نویسندگان
چکیده
This review determines the significance, usefulness, and application of the endomysial antibody test for coeliac disease in clinical practice.
منابع مشابه
Systematic review: the use of serology to exclude or diagnose coeliac disease (a comparison of the endomysial and tissue transglutaminase antibody tests).
BACKGROUND With the appreciation of the high prevalence of coeliac disease there is increasing use of serology in screening asymptomatic people and testing those with suggestive features. AIM To compare the sensitivities and specificities of the endomysial antibody and the tissue transglutaminase antibody tests. METHODS Using electronic databases a search was made for relevant papers using ...
متن کاملEndomysial antibody: is it the best screening test for coeliac disease?
The sensitivities and specificities of the IgA and IgG antigliadin antibody and the IgA antireticulin antibody have been compared with the recently described endomysial antibody directed against the basement membrane of smooth muscle in monkey oesophagus. One hundred and seventeen patients with adult coeliac disease (21 untreated), 84 patients with inflammatory bowel disease, systemic lupus ery...
متن کاملCoeliac disease in primary care: case finding study.
OBJECTIVES To provide evidence of underdiagnosis of coeliac disease and to describe the main presenting symptoms of coeliac disease in primary care. DESIGN Case finding in a primary care setting by testing for coeliac disease by using the endomysial antibody test. SETTING Nine surgeries in and around a market town in central England, serving a population of 70 000. PARTICIPANTS First 1000...
متن کاملIgA-class transglutaminase antibodies in evaluating the efficacy of gluten-free diet in coeliac disease.
OBJECTIVE Serum IgA-class tissue transglutaminase antibody has proved effective in screening for coeliac disease. The response to a gluten-free diet has been assessed on the basis of small-intestinal morphology. We investigated whether the tissue transglutaminase antibody test could substitute biopsy in this respect, and whether the test is better than the endomysial antibody test in follow-up....
متن کاملMalignancy and mortality in a population-based cohort of patients with coeliac disease or "gluten sensitivity".
AIM To determine the risk of malignancy and mortality in patients with a positive endomysial or anti-gliadin antibody test in Northern Ireland. METHODS A population-based retrospective cohort study design was used. Laboratory test results used in the diagnosis of coeliac disease were obtained from the Regional Immunology Laboratory, cancer statistics from the Northern Ireland Cancer Registry ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 76 898 شماره
صفحات -
تاریخ انتشار 2000