Hypertonic saline: A review of the literature and evaluation of its role in resuscitation of traumatic hypovolaemic shock.
نویسنده
چکیده
Hypertonic saline solutions have properties that may be advantageous for resuscitation. In both animal and human studies rapid improvements in cardiovascular status occur when hypertonic saline is administered to hypovolaemic subjects and the possible side effects of hypertonic solutions have not been shown to be of clinical importance. Hypertonic saline certainly has a potential role in resuscitation of hypovolaemic casulaties in the modern military setting.
منابع مشابه
Hypertonic Saline: A Review of the Literature and Evaluation of its Role in Resuscitation of Traumatic Hypovolaemic Shock Maj
Hypertonic saline solutions have properties that may be advantageous for resuscitation. In both animal and human studies rapid improvements in cardiovascular status occur when hypertonic saline is administered to hypovolaemic subjects and the possible side effects of hypertonic solutions have not been shown to be of clinical importance. Hypertonic saline certainly has a potential role in resusc...
متن کاملEffect of ATP-MgCl2-hypertonic solution (NaCl5%) administration on hemorrhagic shock
Introduction: In the recent years, effect of hypertonic solution in resuscitation of shock has been shown by clinical and laboratory studies. On the other hand ATP-MgCl2 is used for better tissue perfusion and cardiac output in shock. The aim of this study is evaluation of ATP-MgCl2 with hypertonic solution in resuscitation of hemorrhagic shock. Materials and Methods: In this experimental stud...
متن کاملAdministration of Large Volume Hypertonic Solutions for Resuscitation of Hemorrhagic Shock in Rabbit
An animal model was designed to study the effect of large volume Hypertonic Solutions (HTS) for resuscitation following a hypovolemic shock. Resuscitation in hypovolemic animals was performed by infusion of 15 ml/kg of normal saline (group I), 5% sodium bicarbonate (NaHCO3) (group II), 5% sodium chloride (NaCI) and 7.5 % NaHCO3 1:1 VN (group III), 5% NaC1 (group IV), and 5% NaCl and 5% serum a...
متن کامل7.5% saline and 7.5% saline/6% dextran for hypovolemic shock.
Conventional resuscitation of traumatic hemorrhagic shock involves the intravenous administration of isotonic (normal saline) or slightly hypotonic (lactated Ringer’s, LR) solution beginning in the prehospital setting. Although not conclusive, prior animal and human studies have suggested that alternative resuscitation with hypertonic saline (7.5%) solutions may reduce mortality in these patien...
متن کاملHypertonic volume therapy: feasibility in the prevention and treatment of multiple organ failure and sepsis.
Small-volume resuscitation by means of bolus infusion of hypertonic saline solutions was first applied for the primary treatment of severe hemorrhagic and traumatic shock and promptly restored central hemodynamics and regional organ blood flow. Mechanisms of action are diverse--i. maintenance of high cardiac output (direct myocardial stimulation; increase in intravascular volume); ii. maintenan...
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ورودعنوان ژورنال:
- Journal of the Royal Army Medical Corps
دوره 140 1 شماره
صفحات -
تاریخ انتشار 1994