Post-injection embolia cutis medicamentosa – Nicolau Syndrome: case report and literature review Embolia cutis medicamentosa pós-injeção – Síndrome de Nicolau: relato de caso e revisão de literatura

نویسندگان

  • Carlos Alberto Araujo Chagas
  • Tulio Fabiano de Oliveira Leite
  • Lucas Alves Sarmento Pires
  • Tulio Fabiano de Oliveira
چکیده

We report on the case of a 40-year-old male who was admitted to the clinic with a large ulcer on his left buttock, 3 days after an intramuscular benzathine penicillin injection. The patient was diagnosed with Nicolau syndrome, a rare vascular complication in which a lesion develops after intramuscular injection. Symptoms are intense pain at the injection site, erythema, and livedoid dermatitis, which leads to necrosis of skin, subcutaneous tissue and muscle tissue. It was described by Nicolau after intramuscular injections of bismuth salt for syphillis therapy. Nicolau syndrome is rare, but its symptoms are devastating and healthcare professionals must be aware of this clinical entity, since intramuscular injections are common procedures for administration of drugs.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Late development of Nicolau syndrome - Case report Síndrome de Nicolau de desenvolvimento tardio - Relato de caso

Nicolau syndrome also known as Embolia cutis medicamentosa and Livedoid dermatitis is a rare complication characterized by tissue necrosis that occurs after injection of medicines. We describe a case of late development of Nicolau syndrome following intra-articular infiltration with corticosteroid.

متن کامل

Nicolau syndrome: report of a case

Nicolausyndrome or embolia cutis medicamentosa is a rare complication of intramuscular injection of some drugs. This syndrome has been reported after injection of NSAIDS, corticosteroids and antibiotics.Here we report a 16-year-old boy who developed this syndrome after intramuscular injection of benzathine penicillin.

متن کامل

[Potomania and osmotic imbalance: permanent cortical visual impairment due to extrapontine myelinolysis].

1. Koller S, Kränke B. Nicolau syndrome following subcutaneous glatiramer-acetate injection. J Am Acad Dermatol. 2011;64:16—7. 2. Kim KK. Nicolau syndrome in patient following diclofenac administration: a case report. Ann Dermatol. 2011;23: 501—3. 3. Gaudez C, Regnier S, Aractingi S, Heinzlef O. Livedolike dermatitis (Nicolau’s syndrome) after injection of Copolymer-1 (Glatiramer acetate). Rev ...

متن کامل

Compartment Syndrome of the Calf Due to Nicolau Syndrome

 We report a case of Nicolau syndrome in a 15 months old girl following of an intramuscular injection of penicillin 6.3.3 in her left buttock. This case is unique because she developed compartment syndrome in her left calf far from her injection site. Her toe’s tips gangrened in the course of her ailment. We hypothesized that the compartment syndrome might be produced by a probable intra-arteri...

متن کامل

Embolia cutis medicamentosa: an unusual adverse reaction to terlipressin

Terlipressin is a synthetic long-acting analog of vasopressin widely used to control variceal bleeding by lowering portal venous pressure. We report an unusual adverse reaction to terlipressin in a 78-year-old patient with esophageal variceal bleeding who developed skin necrosis soon after treatment initiation. Skin biopsy revealed embolia cutis medicamentosa.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016