002 Jurkovic.p65
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Effects of policosanol on gastroprotective action of D-002
Introduction: policosanol, a mixture of higher aliphatic alcohols purified from sugar cane wax, is used to treat hypercholesterolemia. D-002 (Abexol), a mixture of higher aliphatic alcohols from beeswax, is an antioxidant supplement with gastroprotective effects. Then, concomitant intake of D-002 and policosanol may occur in routine practice, so potential pharmacological interactions between th...
متن کاملNB-002, a novel nanoemulsion with broad antifungal activity against dermatophytes, other filamentous fungi, and Candida albicans.
NB-002 is an oil-in-water emulsion designed for use for the treatment of skin, hair, and nail infections. The activity of NB-002 was compared to the activities of the available antifungal drugs against the major dermatophytes responsible for cutaneous infections, Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum spp., as well as 12 other genera of filam...
متن کاملComparative Effects of D-002, Ranitidine and Omeprazole on Acetic Acid-induced Ulcers
D-002, a mixture of six higher aliphatic primary alcohols from beeswax, has been shown to produce gastroprotective effects mediated by increased gastric mucus secretion, improved mucus composition, and the reduction of lipid peroxidation. D-002 is able to heal acetic acid-induced gastric ulcers in rats, but its effects on this model had not been compared with those of proton pump inhibitors (PP...
متن کاملEffects of D-002 on xylene-induced oedema in ear of mice
A well-integrated host inflammatory response is essential in maintaining health and fighting against diseases, but pathological inflammation is linked to many ailments. Non steroidal anti-inflammatory drugs (NSAIDs), used to treat inflammation and pain, are among the most commonly prescribed drugs world over to treat both acute and chronic conditions, but its use is hampered by NSAIDs-related a...
متن کاملEffects of D-002, a mixture of beeswax alcohols, on osteoarthritis symptoms: a randomized placebo-controlled study
Background and purpose: Non selective non-steroidal anti-inflammatory drugs and ciclooxygenase 2 inhibitors provide symptoms relief in osteoarthritis (OA), but produce several adverse effects (AE), which supports the search for other options. D-002, a mixture of higher aliphatic beeswax alcohols, has been shown to produce anti-inflammatory effects experimentally. This double-blind study investi...
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