Synthesis of microfolicoumarin, a constituent of Cedrelopsis microfoliata.

نویسندگان

  • Marellapudi S Ramachandra
  • Somepalli Venkateswarlu
  • Gottumukkala V Subbaraju
چکیده

Microfolicoumarin (1), a prenylcoumarin from Cedrelopsis microfoliata, was synthesized from 2,4,5-trimethoxybenzaldehyde in five steps. 1 did not show significant antioxidative activity, but the key intermediates, esculetin (3) and 5-prenylesculetin (6), exhibited strong antioxidative activity in both the superoxide-radical and 1,1-diphenyl-2-picrylhydrazyl radical-scavenging models.

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عنوان ژورنال:
  • Bioscience, biotechnology, and biochemistry

دوره 68 9  شماره 

صفحات  -

تاریخ انتشار 2004