Alopecia in Lymphomas

Abnormal hair development and regeneration occurs in some skin diseases, including lymphomas when hair follicles are eliminated. Otherwise, neoplastic cells, both malignant and benign, local occurring and metastatic, can cause alopecia of the scalp. In lymphomas alopecia can develop due to direct infiltration by the disease, or it may be a secondary or paraneoplastic manifestation. Total -body hair loss can be diagnosed only in those with generalized erythroderma in mycosis fungoides and Sézary syndrome. Patchy alopecia clinically identical to alopecia areata is revealed in 34% patients suffering from mycosis fungoides or Sézary syndrome. Discreet patch/plaque or follicular lesions is observed within mycosis fungoides lesions in 66%. The involvement of hair follicles usually presents in folliculotropic mycosis fungoides. 65% of patients have alopecia. Follicular mucinosis is frequent in folliculotropic mycosis fungoides. Alopecia is also observed in ichthyosiform mycosis fungoides, syringotropic cutaneous T-cell lymphoma panniculitis-like T-cell lymphoma, primary cutaneous follicle center lymphoma Occipital alopecia areata, occipital and parietal alopecia were observed in Bcell lymphoma. Alopecia is a rare manifestation of Hodgkin’s disease. Alopecia may develop due to therapy and can be even a sign of therapeutical efficacy. *Corresponding author: Irina Khamaganova, Russian National Research Medical University named after N.I. Pirogov, Department of Skin Diseases & Cosmetology, Moscow, Tel: +7 985 998 44 81; Fax: +7 495 770 09 51; E-mail: [email protected] Received January 16, 2014; Accepted January 30, 2014; Published February 07, 2014 Citation: Khamaganova I, Khromova S, Shvec O (2014) Alopecia in Lymphomas. Hair Ther Transplant 4: 117. doi:10.4172/2167-0951.1000117 Copyright: © 2014 Khamaganova I, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.