Lower respiratory infections among hospitalized children in New Caledonia: a pilot study for the Pneumonia Etiology Research for Child Health project.
نویسندگان
چکیده
We conducted a prospective pilot study over a 1-year period in New Caledonia in preparation for the Pneumonia Research for Child Health (PERCH) project. The pathogens associated with hospitalized lower respiratory infections in children were identified through the use of culture of induced sputum and blood, urinary antigen detection, polymerase chain reaction (PCR) on respiratory specimens, and serology on paired sera. Respiratory viruses were detected on respiratory specimens by immunofluorescence and PCR, and by serology on paired sera. Pathogens were detected in 87.9% of the 108 hospitalized cases. Viruses represented 81.6% of the 152 pathogens detected. Respiratory syncytial virus and rhinovirus were the most frequent, accounting for 32.2% and 24.3% of the pathogens identified, respectively. Only 26.3% of 99 induced sputum specimens collected were determined to be of good quality, which may be a consequence of the collection method used.
منابع مشابه
Lower respiratory infections (LRIs) etiologies in hospitalized children in New Caledonia: a PERCH pilot study
Background Worldwide, lower respiratory infections (LRIs) are the most frequent cause of death in children under 5 years. The Pneumonia Etiology Research for Child Health (PERCH) project is a large, multi-center case-control study of hospitalized pediatric patients with severe LRI to determine the etiology and risk factors associated with the syndrome. By applying modern tools with standardized...
متن کاملLower respiratory infections among hospitalized children in New Caledonia and relevance of induced sputum analysis
We conducted a prospective study over a one year period in New Caledonia to determine the pathogens associated with hospitalized lower respiratory infections (LRI) in children. pa st eu r-0 07 69 46 5, v er si on 1 2 Ja n 20 13
متن کاملعفونت های حاد تنفسی در کودکان
Acute Respiratory tract infections (ART!) are one of the most common problems encountered in childhood. In this article, epidemiology of ART! in the pediatric ward of Talegheni Medical center during a 5 year period from 1988 to 1993 was reviewed. 191 children were hospitalizid with ARTI. 184 (96.3%) suffered from LRT!, and of these, 150 patients had pneumonia (78.5%), 22 had Croups (11.5%), 12 ...
متن کاملEvaluation of epidemiologic, clinical and laboratory factors of hospitalized children with pneumonia
Introduction: Pneumonia is one of the major causes of mortality in acute respiratory infections of children. Most of death cases due to pneumonia among children, occurred several days after clinical manifestation which is due to delay of remedy or indiscrimination. Our aim, in this study, is evaluation of epidemiologic, clinical and laboratory factors of hospitalized children with pneumon...
متن کاملProcedures for collection of induced sputum specimens from children.
In most settings, sputum is not routinely collected for microbiological diagnosis from children with lower respiratory disease. To evaluate whether it is feasible and diagnostically useful to collect sputum in the Pneumonia Etiology Research for Child Health (PERCH) study, we reviewed the literature on induced sputum procedures. Protocols for induced sputum in children were collated from publis...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
دوره 54 Suppl 2 شماره
صفحات -
تاریخ انتشار 2012