OECD GUIDELINE FOR THE TESTING OF CHEMICALS In Vitro Membrane Barrier Test Method for Skin Corrosion

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چکیده

1. Skin corrosion refers to the production of irreversible damage to the skin, manifested as visible necrosis through the epidermis and into the dermis, following the application of a test material [as defined by the United Nations (UN) Globally Harmonized System of Classification and Labelling of Chemicals (GHS)] (1). This Test Guideline provides an in vitro procedure by which the assessment of corrosivity is not carried out in live animals.

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تاریخ انتشار 2006