Rotavirus infection: an unrecognised disease in Nepal.
نویسنده
چکیده
Rotavirus is the most common cause of acute infectious gastroenteritis in young children and is associated with substantial morbidity and mortality worldwide, mostly in developing countries. The global rotavirus disease burden has prompted study on their basic research, molecular epidemiology and vaccine development. Little is known about rotavirus infection among health professionals in Nepal. This article summarises basic and clinical features, treatment and prevention, epidemiological pattern, challenges and recommendations of human rotavirus infections in Nepal.
منابع مشابه
Human rotavirus associated diarrhea and strain diversity in Nepal.
Two new rotavirus vaccines were recently introduced to the market and have shown a tremendous impact in reducing severe diarrhea due to rotavirus in children. Diarrheal disease is a common cause of morbidity and mortality among Nepalese children. In anticipation of a rotavirus vaccine in Nepal, we systematically reviewed published articles on rotavirus infection in Nepal. Literatures were searc...
متن کاملTrends of rotavirus in Nepal.
BACKGROUND Rotavirus gastroenteritis is the major cause of morbidity and mortality in infants and young children worldwide. Safe and effective rotavirus vaccine is needed to have significant impact on severe rotavirus gastroenteritis. Currently, two live oral rotavirus vaccines have been licensed in many countries. Knowledge on distribution of human rotavirus of G and P types are essential befo...
متن کاملEpidemiology of Rotavirus Infection in Certain Countries
Abstract Acute diarrhea with severe dehydration has been a major worldwide cause of death in children younger than 5 years of age. Etiological studies of gastroenteritis have shown that rotavirus causes 40–50% of acute diarrhea among infants and children in both developing and developed nations. Numerous epidemiologic studies in the US and the World Health Organization have docu...
متن کاملPrevalence of group A genotype human rotavirus among children with diarrhoea in Nepal, 2009-2011.
BACKGROUND Rotavirus as a causative agent of childhood diarrhea is known to cause serious illness among children less than 5 years of age. This study examined the epidemiology of rotavirus disease burden and diversity of G and P genotypes of rotavirus in Nepal. METHODS Stool samples were tested for rotavirus by Enzyme Immuno Assay and Group A rotaviruses were detected by using both ELISA and ...
متن کاملA study of diarrhoea among children in eastern Nepal with special reference to rotavirus.
PURPOSE To examine the incidence of Rotavirus infection in children below five years of age. METHODS Faecal samples from 160 children under five years of age with acute gastroenteritis were collected over a period of one year from July 1999 to June 2000. These were studied for the presence of Rotavirus antigen by enzyme immuno assay (EIA). RESULTS Rota antigen could be detected in 62 (38.7%...
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ورودعنوان ژورنال:
- Kathmandu University medical journal
دوره 8 29 شماره
صفحات -
تاریخ انتشار 2010