Fixed drug eruptions caused by cross-reactive quinolones
نویسندگان
چکیده
Fixed drug eruptions (FDE) are the common dermatological adverse drug reaction accounts for 16-21% of all cutaneous drug reactions in India. Drugs most frequently implicated in FDE are antimicrobials, anticonvulsants, and nonsteroidal antiinflammatory drugs. Here, we report a rare case of bullous FDE due to ciprofloxacin followed by ofloxacin administration.
منابع مشابه
Unexpected cross-reactivity in a cat-allergy patient. An allergic reaction at the circus.
1. Brahimi N, Routier E, Raison-Peyron, Tronquoy AF, PougetJasson, Amarger S, et al. A three-year-analysis of fixed drug eruptions in hospital settings in France. Eur J Dermatol. 2010;20:461--4. 2. Lee AY. Fixed drug eruptions. Incidence, recognition, and avoidance. Am J Clin Dermatol. 2000;1:277--85. 3. Shiohara T. Fixed drug eruption: pathogenesis and diagnostic tests. Curr Opin Allergy Clin ...
متن کاملPatch testing in fixed drug eruptions--a 20-year review.
BACKGROUND The fixed drug eruption is a common adverse drug reaction. Clear identification of the culprit drug is not always possible in the clinical setting, and oral rechallenge may induce new lesions or severe reactions. OBJECTIVES The main purpose of this study was to evaluate the diagnostic value of patch testing in establishing an aetiological diagnosis in fixed drug eruptions. METHOD...
متن کاملOne Drug - Two Similar Reactions . Report of cases of Ciprofloxacin induced Stevens - Johnson Syndrome and Bullous fixed drug eruption
Ciprofloxacinis a broad spectrum quinolone antibiotic which is used to treat a wide variety of infections, especially those likely to be caused by Gramnegative bacteria. It acts by inhibiting DNA gyrase and topoisomerase IV enzymes which is necessary to separate bacterial DNA, thereby inhibiting cell division. It induces panoply of drug reactions ranging from an urticarial eruption to a lethal ...
متن کاملA Case of Self-treatment Induced Recurrent Fixed Drug Eruptions Associated with the Use of Different Fixed Dose Combinations of Fluoroquinolone-Nitroimidazole
A young male patient used fixed dose combinations of different fluoroquinolones and nitroimidazoles several times in the last few years for self-treating repeated episodes of diarrhea and loose motion. Each time, he experienced fixed drug eruptions that increased in number and severity on subsequent occasions. Suspecting association between the drug and the rashes, the patient each time discont...
متن کاملFixed drug eruption caused by tadalafil - Case report*
UNLABELLED Fixed drug eruptions (FDE) are commonly reported type of mucocutaneous drug eruption. The aim of this paper is to present a patient with multiple mucocutaneous erythema fixum type lesions caused by oral tadalafil use. A short course of topical corticosteroid therapy resulted in complete resolution of all lesions leaving residual hyperpigmentation of the involved skin sites. Mucosal o...
متن کامل