Cholecalciferol and 25-hydroxyvitamin D concentrations in adults with cystic fibrosis.
نویسندگان
چکیده
منابع مشابه
Cholecalciferol significantly increases 25-hydroxyvitamin D concentrations in adults with cystic fibrosis.
BACKGROUND Vitamin D deficiency is increasingly being recognized and treated in patients with cystic fibrosis, although the treatment guidelines are not proven and the effectiveness of vitamin D preparations is untested. OBJECTIVES The aims of this study were to determine the prevalence of 25-hydroxyvitamin D [25(OH)D] deficiency in a large cohort of adults with cystic fibrosis and to evaluat...
متن کاملPilot study of vitamin D supplementation in adults with cystic fibrosis pulmonary exacerbation
UNLABELLED BACKGROUND Vitamin D insufficiency is common in cystic fibrosis (CF) and vitamin D repletion may have an important role in improving clinical outcomes in CF. This randomized, placebo-controlled, pilot study examined the feasibility and impact of a single, large dose of cholecalciferol on vitamin D status and clinical outcomes in subjects with CF. METHODS Thirty ...
متن کاملFree 25-Hydroxyvitamin D Concentrations in Cystic Fibrosis.
BACKGROUND Vitamin D deficiency is common in cystic fibrosis (CF), but there is no previous data on free 25-hydroxyvitamin D (25[OH]D) in CF or in relation to healthy individuals. METHODS We assessed total serum 25(OH)D concentration by chemiluminescence and serum free 25(OH)D concentration by both direct measurement (ELISA) and calculation, using serum albumin and vitamin D binding protein (...
متن کاملVitamin D and parathyroid hormone and bone mineralisation in adults with cystic fibrosis.
Vitamin D and parathyroid hormone concentrations were assessed in 31 adults with cystic fibrosis (mean age 24, range 17-52 years), in 28 of whom the bone mineral index in the forearm was also determined. Serum 25-hydroxyvitamin D was subnormal in eight patients, of whom five were receiving vitamin D supplements in standard doses. 1,25-dihydroxyvitamin D and parathyroid hormone concentrations sh...
متن کاملVitamin D and inflammation
Several studies found an inverse relationship between 25-hydroxyvitamin D [25(OH)D] and markers of inflammation. A controversy exists as to whether vitamin D lowers inflammation or whether inflammation lowers 25(OH)D concentrations. Certainly 25(OH)D concentrations fall after major surgery. However, is this due to inflammation lowering 25(OH)D or is 25(OH)D being metabolically cleared by the bo...
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ورودعنوان ژورنال:
- The American journal of clinical nutrition
دوره 87 1 شماره
صفحات -
تاریخ انتشار 2008