Primary growth hormone insensitivity and psychomotor delay

نویسندگان

  • Inma Castilla-Cortazar
  • Julieta Rodríguez De Ita
  • Gabriel A Aguirre
  • Joel Rodríguez-Rivera
  • Mariano García-Magariño
  • Irene Martín-Estal
  • Óscar Flores-Caloca
  • Carlos Diaz-Olachea
چکیده

We report a case of short stature irresponsive to growth hormone (GH) replacement therapy. Low GH response to provocative tests and undetectable IGF-1 levels had suggested GH deficiency, while response to therapy indicated GH insensitivity. Molecular evaluation of the GH/IGF-1 axis should be performed in these cases to improve diagnosis and therapy.

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2018