Fospropofol disodium (lusedra) injection for anesthesia-care sedation: a clinical review.

نویسندگان

  • Ramy Boules
  • Andrew Szkiladz
  • Anna Nogid
چکیده

Fospropofol disodium (Lusedra) for anesthesia sedation.

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1 . Jantz MA . The old and the new of sedation for bronchoscopy . Chest . 2009 ; 135 ( 1 ): 4 6 . 2 . US Food and Drug Administration. Lusedra (Fospropofol disodium) prescribing information. http :// www . accessdata . fda . gov / drugsatfda_docs / label / 2008 / 022244lbl . pdf . Accessed July 31, 2009 . 3 . Silvestri GA , Vincent BD , Wahidi MM , Robinette E , Hansbrough JR , Downie GH . A ph...

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1 Jantz MA. The old and the new of sedation for bronchoscopy. Chest 2009; 135:4–6 2 Silvestri GA, Vincent BD, Wahidi MM, et al. A phase 3, randomized, double-blind study to assess the efficacy and safety of fospropofol disodium injection for moderate sedation in patients undergoing flexible bronchoscopy. Chest 2009; 135:41– 47 3 Cohen LB. Clinical trial: a dose-response study of fospropofol dis...

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Fospropofol Disodium Injection: A Review of its Use as a sedative-hypnotic Agent for Monitored Anesthesia care (MAc) sedation in Adult patients Undergoing Diagnostic or Therapeutic procedures

Fospropofol, a phosphorylated prodrug version of the popular induction agent propofol, is hydrolyzed in vivo to release active propofol, formaldehyde, and phosphate. Pharmacodynamic studies show fospropofol provides clinically useful sedation and EEG/BIS suppression while causing significantly less respiratory depression than propofol. Pain at the injection site, a common complaint with propofo...

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Perspectives on the Role of Fospropofol in the Monitored Anesthesia Care Setting

Monitored anesthesia care (MAC) is a safe, effective, and appropriate form of anesthesia for many minor surgical procedures. The proliferation of outpatient procedures has heightened interest in MAC sedation agents. Among the most commonly used MAC sedation agents today are benzodiazepines, including midazolam, and propofol. Recently approved in the United States is fospropofol, a prodrug of pr...

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عنوان ژورنال:
  • P & T : a peer-reviewed journal for formulary management

دوره 37 7  شماره 

صفحات  -

تاریخ انتشار 2012