Application of Sonochemistry for Formation of Nanosized Silver and Silver/Hydroxyapatite Composite Particles

Development of nanotechnology during last few decades gave significant contribution to different areas of research especially in biomedical sciences and improved characteristics of many biomaterials allowing their commercial application [1,2]. One of the representative examples is the development of nanomedicine, a new field of medical research which opened the possibility for interactions between nanomaterials and pathogens at the same scale of size [3]. This approach allowed development of nano-therapeutics, biosensors and point-of-care molecular diagnostic devices resulting in target, localized and more efficient medication [4]. So far, different techniques are applied for formation of these materials. Among them, sonochemical synthesis can be separated as a method based on the high temperature and pressure combined with intensive mixing induced by acoustic cavitation and micro jets. This method enables control over size, morphology and nano-/micro-structure of materials that are often unavailable by conventional methods [5].