Multiple Sclerosis with Early Childhood Onset
نویسندگان
چکیده
S U M M A R Y — A 2 y e a r o l d b o y w a s a d m i t t e d o w i n g t o a s u b a c u t e e p i s o d e o f a t a x i c g a i t a n d h e a r i n g d e f i c i t . C o m p u t e r i z e d t o m o g r a p h y ( C T ) w a s n o r m a l a n d c e r e b r o s p i n a l f l u i d ( C S F ) a n a l y s i s r e v e a l e d g a m m a g l o b u l . n s l e v e l o f 1 5 . 4 % ( n o r m a l 7 t o 1 4 % ) . T h e r e w a s s p o n t a n e o u s r e m i s s i o n a f t e r 7 m o n t h s . A t 5 y e a r s o f a g e t h e b o y i n c u r r e d a s e c o n d e p i s o d e w i t h p r e d o m i n a n t l y r i g h t a p e n d i c u l a r a t a x i a a n d t o n i c g a z e d e v i a t i o n t o t h e r i g h t s i d e . C T s h o w e d a l o w d e n s i t y l e s i o n i n t h e w h i t e m a t t e r a d j a c e n t t o t h e r i g h t f r o n t a l h o r n . V i s u a l a n d a u d i t o r y e v o k e d p o t e n t i a l s w e r e a b n o r m a l . C S F r e v e a l e d a m i l d i n c r e a s e i n g a m m a g l o b u l i n s l e v e l o f 1 4 . 5 % w i t h a n a b n o r m a l T l y m p h o c y t e s u b s e t s s t u d y . T h e c o m b i n a t i o n o f v i s u a l , c e r e b e l l a r , b r a i n s t e m a n d p a r a v e n t r i c u l a r l e s i o n s w i t h c l e a r r e m i s s i o n s a n d e x a c e r b a t i o n s , s u p p o r t e d b y C T , C S F a n d e v o k e d p o t e n t i a l s f i n d i n g s s u g g e s t s t h e d i a g n o s i s o f m u l t i p l e s c l e r o s i s e v e n a t t h i s e a r l y a g e .
منابع مشابه
Clinical and Epidemiological Features of Early and Adult Onset Multiple Sclerosis in Hamedan, Iran, 2004–2005
Mazaheri Sh1, Fazlian MM2, Hossein Zadeh A3 1. Assistant Professor, Department of Neurology, Faculty of medicine, Hamedan University of Medical Sciences 2. General practitioner, Specialty and Subspecialty Hospital of Besat, Hamedan University of Medical Sciences 3. General practitioner, Hamedan Health Center Abstract Background: Multiple Sclerosis (MS) is one of the most common causes of chr...
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