Citrullinated Chemokines in Rheumatoid Arthritis
نویسنده
چکیده
s accepted to national meetings: 1. Yoshida K, Campbell PL, Amin MA, Koch AE, Fox DA, Ruth JH: Citrullination of ENA78/CXCL5 changes its receptor affinity from CXCR2 to CXCR1 and induces monocyte migration. Arthritis Rheum. 65 S10:327, 2013. 2. Edhayan G, Ha CM , Ohara RA, Isozaki T, Amin MA, Arbab AS, Tsou PS, Campbell PL, Schiopu E, Khanna D, Morgan R, Friday SC, Fox DA, Ruth JH: Inflammatory Properties of Inhibitor of DNA Binding 1 as a Unique Fibroblast Derived Nuclear Protein. Arthritis Rheumatol. 66 S10:863, 2014. 3. Ohara RA, Edhayan G, Ha CM, Amin MA, Arbab AS, Campbell PL, Fox DA, Ruth JH: Evidence for citrullination of the nuclear transcription factor Inhibitor of DNA Binding 1 (Id1) in Rheumatoid Arthritis. Arthritis Rheumatol: 66 S10:189, 2014. 4. Ohara RA, Edhayan G, Stinson WA, Campbell PL, Remmer HA, Amin MA, Fox DA, Ruth JH: Evidence for Citrullinated Inhibitor of DNA Binding 1 (Id1) as a Novel Autoantigen Candidate in Rheumatoid Arthritis. Arthritis Rheumatol In press. 5. Edhayan G, Ha CM, Ohara RA, Isozaki T, Amin MA, Arbab AS, Campbell PL, Morgan R, Stinson WA, Friday SC, Fox DA, Ruth JH: Inhibitor of DNA Binding 1 as a Fibroblast Derived Inflammatory Angiogenic Agonist in Rheumatoid Arthritis. Arthritis Rheumatol In press. 6. Ohara RA, Lepore N, W. Stinson WA, Edhayan G, Campbell PL, Arwani S, Morgan RL, Ruth JH, Koch AE, Fox DA, Amin MA: Citrullinated ENA78/CXCL5 Induces Monocyte Migration via JNK and NFκB Signaling Pathways. Arthritis Rheumatol In press. 7. Inventions, Patents and Licenses
منابع مشابه
Citrullination of epithelial neutrophil-activating peptide 78/CXCL5 results in conversion from a non-monocyte-recruiting chemokine to a monocyte-recruiting chemokine.
OBJECTIVE To examine whether the citrullinated chemokines epithelial neutrophil-activating peptide 78 (ENA-78)/CXCL5, macrophage inflammatory protein 1α/CCL3, and monocyte chemotactic protein 1/CCL2 are detected in the biologic fluid of patients with rheumatoid arthritis (RA), and if so, to determine the biologic activities of these chemokines. METHODS Recombinant human chemokines were citrul...
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Background: Controlling the pulmonary involvement, as one of the most common extra-articular consequences in rheumatoid arthritis (RA), can improve the life quality and survival rate of patients. This study aimed to evaluate the correlation between disease-related inflammatory factors and the severity and type of lung involvement in patients, which is a practical step toward early detection and...
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Abstract Background: Rheumatoid Arthritis, (RA) is a chronic inflammatory autoimmune disease with a progressive course requiring early diagnosis and treatment. The value of anti-cyclic citrullinated peptide antibodies (Anti-CCP) in the diagnosis of RA has been shown in several studies. The present study was designed to determine and compare the diagnostic value of Anti-CCP and rheumatoid fac...
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Anti-cyclic peptide antibodies (CCP/ACPA) are directed towards synthetic citrullinated peptides and are specific markers in diagnosis of Rheumatoid arthritis. This study aimed to compare the values and acuracy of the test in anticyclic citrullinated peptides (Anti-CCP /ACPA) antibodies, rheumatoid factor (RF), C-reactive protein (CRP) and disease activity index (PASI) in early diagnosis of untr...
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