Further studies on the mechanism of action of hydroxyurea.
نویسنده
چکیده
Addition of the four deoxyribonucleosides in vitro to 6C3HED mouse ascites tumor stimulates 32P incorporation into DNA and depresses incorporation into RNA at concentrations greater than 10~4 M. The four ribonucleosides stimulate incorporation into both DNA and RNA. Hydroxyurea blocks the ribonucleoside stimulation of 32P incorporation into DNA but not RNA. The inhibition of 32P incorporation into DNA by hydroxyurea
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ورودعنوان ژورنال:
- Cancer research
دوره 28 6 شماره
صفحات -
تاریخ انتشار 1968