Nuclear receptor corepressors
نویسنده
چکیده
The ability of NR LBDs to transfer repression function to a heterologous DNA binding domain, and the cross-squelching of repression by untethered LBDs, has suggested that repression is mediated by interactions with putative cellular corepressor proteins. The yeast-two hybrid screen for protein interactors has proven to be the key to the isolation and characterization of corepressors. This short review will focus on N-CoR and SMRT.
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ورودعنوان ژورنال:
- Nuclear Receptor Signaling
دوره 1 شماره
صفحات -
تاریخ انتشار 2003