Nanomaterials: A challenge for toxicologists
نویسندگان
چکیده
The new and unique applications offered by nanotechnology in diverse areas have made it so popular that it is being applied today in almost all aspects of daily life. Although the small size and subsequent larger surface area of nanoparticles (NPs) endow them with some highly useful and specific properties, it also renders them more active leading to unexpected and unanticipated consequences on interaction with biological systems. The concern over the probable adverse effects of nanomaterials on living systems has given rise to ‘nanotoxicology’. However, nanotoxicology has lagged far behind nanotechnology due to a number of experimental challenges and issues faced in designing studies involving toxicological assessment of nanomaterials. This review, therefore addresses some of the issues pertaining to nanomaterial toxicology with respect to nanomaterial characterization, agglomeration, dose metric and surface coating.
منابع مشابه
Nanotoxicology for safe and sustainable nanotechnology.
Nanotechnology is the term given to those areas of science and engineering where the phenomena take place at nanoscale dimensions. Nanoparticles are particles with <100 nm in one dimension. They have different physical, chemical, electrical and optical properties than those that occur in bulk samples of the same material. Understanding these nanoscale properties and finding ways to engineer new...
متن کاملForum series: research strategies for safety evaluation of nanomaterials.
To properly assign mechanisms or causes for toxic effects of nanoscale materials, their properties and characteristics both outside and within the biological environment must be well understood. Scientists have many tools for studying the size, shape, and surface properties of particulates outside of the physiological environment; however, it is difficult to measure many of these same propertie...
متن کاملDifferential Distribution and Toxicity of Nanomaterials In Vivo
Opportunity for Nanotechnology: The innovative field of nanotechnology is most likely to gain societal acceptance if environmental and human health considerations are thoroughly investigated and those results are used to optimize safety and performance together to produce effective and non-toxic profitable technologies. Industrial and scientific communities must work together to integrate toxic...
متن کاملNanotoxicology: characterizing the scientific literature, 2000–2007
Understanding the toxicity of nanomaterials and nano-enabled products is important for human and environmental health and safety as well as public acceptance. Assessing the state of knowledge about nanotoxicology is an important step in promoting comprehensive understanding of the health and environmental implications of these new materials. To this end, we employed bibliometric techniques to c...
متن کاملScientists’ Understandings of Risk of Nanomaterials: Disciplinary Culture Through the Ethnographic Lens
There is a growing literature on how scientific experts understand risk of technology related to their disciplinary field. Previous research shows that experts have different understandings and perspectives depending on disciplinary culture, organizational affiliation, and how they more broadly look upon their role in society. From a practice-based perspective on risk management as a bottom-up ...
متن کامل