Biosensor development.

نویسندگان

  • C Ziegler
  • W Göpel
چکیده

Current biosensor developments can be summarised by different trends. For traditional enzymatic biosensors such as glucose sensors, steady improvements of well known basic principles have been made in order to achieve better sensor stability. On the other hand, new affinity sensors such as nucleic acid sensors, transmembrane sensors, and sensors utilising whole cells or even cell networks have become of increasing interest. New ways to miniaturise biosensors and to control their interfaces down to the molecular level have been introduced (the bioelectronics approach). High-throughput screening based on various signal transduction principles has become of increasing importance.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of Different Functionalized CNTs for Development of Choline Amperometric Biosensor

Choline oxidase (ChOx) was chosen as a model enzyme for evaluating the performance of CNTs’ functional groups for development of enzyme electrodes. CNTs were functionalized with carboxylic acid, amine or amide groups. Carboxylic acid, amine and amide functionalized CNTs were obtained by acid treatment, ethylenediamine or tetraethylenepentamine chemically modification and ammonia plasma treatmen...

متن کامل

Recent Advance of Biosensor Instruments in Pesticide Residues Rapid Detection

In recent years, efforts have been reported to develop portable biosensor instrument in the detection felid such like pesticide residues. There is a great potential in the applications of biosensor technologies for rapid detection of pesticide residues in food and environment. In other words, meantime, biosensor instrument has wide application in the instruments market. This paper presents an o...

متن کامل

Protein Engineering for Biosensor Development Abstract Protein Engineering for Biosensor Development

Protein Engineering for Biosensor Development by Aleksandr Ettore Miklos Department of Biochemistry Duke University Date:_______________________ Approved: ___________________________ Homme W. Hellinga, Supervisor ___________________________ Bruce R. Donald ___________________________ Terrence G. Oas ___________________________ David C. Richardson An abstract of a dissertation submitted in parti...

متن کامل

Cytochrome C Biosensor—A Model for Gas Sensing

This work is about gas biosensing with a cytochrome c biosensor. Emphasis is put on the analysis of the sensing process and a mathematical model to make predictions about the biosensor response. Reliable predictions about biosensor responses can provide valuable information and facilitate biosensor development, particularly at an early development stage. The sensing process comprises several in...

متن کامل

Highly sensitive detection of telomerase using a telomere-triggered isothermal exponential amplification-based DNAzyme biosensor.

A telomere-triggered isothermal exponential amplification-based DNAzyme biosensor is developed for highly sensitive detection of telomerase in cancer cells even at the single-cell level. This biosensor can be further applied for the screening of telomerase inhibitors for anticancer drug development.

متن کامل

Optimization of a genetically encoded biosensor for cyclin B1-cyclin dependent kinase 1.

Fluorescent protein (FP)-based biosensors have revolutionized the ability of researchers to monitor enzyme activities in live cells. While the basic design principles for FP-based biosensors are well established, first-generation biosensor constructs typically suffer from relatively low fluorescence responses that limit their general applicability. The protein engineering efforts required to su...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Current opinion in chemical biology

دوره 2 5  شماره 

صفحات  -

تاریخ انتشار 1998