Clindamycin-Resistant Clone of Clostridium difficile PCR Ribotype 027, Europe
نویسندگان
چکیده
Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 14, No. 9, September 2008 1485 Mayboun Heuangvongsy, Chanpheng Thammavong, Bouachanh Rasachack, Bounkong Syhavong, Nicholas J. White, Suriyasack Thongpaseuth, Anisone Changthongthip, Viengmone Davong, Olay Lattana, Manivanh Vongsouvath, Kai-amporn Keopaseuth, Sengmani Symanivong, Viengmala Sihalath, and Alatsany Chandara for participating in the study; and Ponmek Dalaloy and Sommone Phounsavath for support.
منابع مشابه
Antimicrobial-resistant strains of Clostridium difficile from North America.
A total of 316 toxigenic Clostridium difficile clinical isolates of known PCR ribotypes from patients in North America were screened for resistance to clindamycin, metronidazole, moxifloxacin, and rifampin. Clindamycin resistance was observed among 16 different ribotypes, with ribotypes 017, 053, and 078 showing the highest proportions of resistance. All isolates were susceptible to metronidazo...
متن کاملA case of Clostridium difficile-associated disease due to the highly virulent clone of Clostridium difficile PCR ribotype 027, March 2007 in Germany.
Increasing rates of Clostridium difficile-associated disease (CDAD) have been reported from North America since 2003. This increase is associated with the emergence and spread of a particular strain of C. difficile characterised as PCR ribotype 027 or pulsotype NAP1. This epidemic strain produces toxins A and B and the binary toxin, is resistant to erythromycin and the newer fluoroquinolones, a...
متن کاملAn investigation of the subtype diversity of clinical isolates of Irish Clostridium difficile ribotypes 027 and 078 by repetitive-extragenic palindromic PCR.
A repetitive-extragenic palindromic PCR (rep-PCR) subtyping method (DiversiLab) in conjunction with ribotyping, toxinotyping and antimicrobial-susceptibility testing was used to detect subtypes within Clostridium difficile ribotypes 027 and 078. Clinical isolates of ribotypes 027 (toxinotype III) (n = 30) and 078 (toxinotype V) (n = 23) were provided by health-care facilities across the Republi...
متن کاملUpdate of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008.
Outbreaks of Clostridium difficile infections (CDI) with increased severity, high relapse rate and significant mortality have been related to the emergence of a new, hypervirulent C. difficile strain in North America and Europe. This emerging strain is referred to as PCR ribotype 027 (Type 027). Since 2005, individual countries have developed surveillance studies about the spread of type 027.C....
متن کاملEmergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage.
Clostridium difficile is the most common cause of antibiotic-associated diarrhoea worldwide. Over the past 10 years, the incidence and severity of disease have increased in North America and Europe due to the emergence of a hypervirulent clone designated PCR ribotype 027. In this study, we sought to identify phenotypic differences among a collection of 26 presumed PCR ribotype 027 strains from ...
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ورودعنوان ژورنال:
- Emerging Infectious Diseases
دوره 14 شماره
صفحات -
تاریخ انتشار 2008