A prospective study of time to healing and hypertrophic scarring in paediatric burns: every day counts
نویسندگان
چکیده
BACKGROUND It is commonly accepted that burns taking longer than 3 weeks to heal have a much higher rate of hypertrophic scarring than those which heal more quickly. However, some of our patients develop hypertrophic scars despite healing within this 3-week period. METHODS We performed a prospective study of 383 paediatric burns treated non-operatively at a regional burns centre over a 2-year period from May 2011 to April 2013. Scar assessment was performed by a senior burns therapist using the Vancouver Scar Scale. RESULTS Overall rates of hypertrophic scarring were 17.2%. Time to healing was the strongest predictor of developing hypertrophic scarring, and the earliest hypertrophic scar developed in a patient who was healed after 8 days. The risk of hypertrophic scarring was multiplied by 1.138 for every additional day taken for the burn wound to heal. There was a trend towards higher rates of hypertrophic scarring in non-white skin types but this did not reach statistical significance. CONCLUSIONS The risk of hypertrophic scarring increases with every day and, therefore, every effort should be made to get the wound healed as quickly as possible, even within the traditional 3-week period usually allowed for healing. We believe that the traditional dogma of aiming for healing within 3 weeks is overly simplistic and should be abandoned: in paediatric burns, every day counts. TRIAL REGISTRATION Not applicable.
منابع مشابه
The role of the TGF-β family in wound healing, burns and scarring: a review.
It is estimated worldwide that over 6 million people per annum experience a burn injury. Despite advances in management and improved survival rates, the incidence of hypertrophic scarring remains high. These scars are particularly common after burns and are often raised, red, hard and may cause abnormal sensations. Such pathological scarring can lead to severe functional impairment, psychologic...
متن کاملWound dressing of second degree burn by chamomile cream and Silver sulfadiazine cream; the effects on wound healing duration; a triple blind RCT
Background: Burn is the fourth most prevalent trauma around the world that many people are affected by it every year. One of the common methods of healing burn wounds is the use of Silver sulfadiazine cream 1%, the most important complication of which is the delay in healing of the wound. Objective: This study was done in order to identify and evaluate effective drugs in the treatment of burn w...
متن کاملComparison of Albizia Julibressin and Silver Sulfadiazine in Healing of Second and Third Degree Burns
BACKGROUND Large numbers of population suffer from burn annually. The promising treatment of burn has not been identified yet. Albizia julibressin (A. julibressin) in Fabaceae family is popular for its antiseptic activity. This prospective study was designed to compare the wound healing effects of A. julibressin gel (AG) with silver sulfadiazine (SSD). METHODS This single blind clinical tria...
متن کاملThe Study of Hypericum perforatum extract on wound healing in rabbit
Wound healing is a natural reaction to injury witch results in restoration of tissue integrity. Repair consists of four phases: inflammation, re-epithelialization, angiogenesis, fibroblast recruitment and scarring. In this study the healig effect of Hypericum perforatum extract was investigated on open wound. Hydroalcoholic extract of Hypericum P. was prepared by maceration method. Newzeland ra...
متن کاملThe Study of Hypericum perforatum extract on wound healing in rabbit
Wound healing is a natural reaction to injury witch results in restoration of tissue integrity. Repair consists of four phases: inflammation, re-epithelialization, angiogenesis, fibroblast recruitment and scarring. In this study the healig effect of Hypericum perforatum extract was investigated on open wound. Hydroalcoholic extract of Hypericum P. was prepared by maceration method. Newzeland ra...
متن کامل