Antigenic structure of foot and mouth disease virus type A22 (Indian isolates).
نویسندگان
چکیده
Variations in foot and mouth disease virus are due to amino acid substitutions in the VP1, which is a major immunogen. Analysis of this hypervariable region is essential to know the antigenic structure of the serotype and is necessary to select a suitable vaccine strain. FMDV type A22 is one of the four prevailing virus types for which the vaccine is used regularly. To understand the antigenic structure of this type, carboxy- terminal region of VP1 from two field isolates and vaccine virus were sequenced and analysed. The results indicate that, Indian A22 has distinct antigenic structure.
منابع مشابه
Serological comparison of type A foot and mouth disease virus isolates from Thailand.
Antigenic variation of type A foot and mouth disease (FMD) virus in Thailand was examined using a total of 82 field viruses isolated between 1986 and 1989. A two-dimensional serum microneutralisation test was used to compare these isolates to a reference strain, A15 Bangkok 1960 (A BKK/60). Viruses regarded as unrelated to A BKK/60 were compared to another reference strain, A22 Nakhon Pathom 19...
متن کاملStudies on foot and mouth disease in the eastern region of Abu Dhabi, United Arab Emirates.
The present paper describes the status of foot and mouth disease (FMD) in the eastern region of Abu Dhabi, United Arab Emirates, over a three-year period from 1987 to 1989. The disease was prevalent among the various livestock populations in the study area. Type O appeared to be most prevalent followed by types A and Asia 1 which were recorded at lower incidences. Type C was not recorded during...
متن کاملA comparison of type O foot and mouth disease virus field isolates from northern Thailand.
A survey of type O foot and mouth disease (FMD) virus isolates from northern Thailand was undertaken to determine the relationship between field viruses and the vaccine in use, and to gauge the range of antigenic variation among field viruses. Isolates were collected from the two most recent epizootics, 1986-1987 and 1989-1990, and assessed using a two-dimensional neutralisation test to determi...
متن کاملComparative immunogenecity of foot and mouth disease virus antigens in FMD-haemorrhagic septicaemia combined vaccine and FMD vaccine alone in buffalo calves.
Humoral immune response was evaluated by monitoring the serum antibody titres and virus specific IgM titres against Foot and Mouth Disease (FMD) virus antigens in serum samples obtained from different groups of calves inoculated with combined vaccine or FMD vaccine alone, on 0, 7, 14, 21, 28, 42 and 56 days post-vaccination (DPV). The cellular immune response was monitored by MTT based lymphopr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Indian journal of experimental biology
دوره 36 1 شماره
صفحات -
تاریخ انتشار 1998