Selective laryngeal adductor denervation-reinnervation: a new surgical treatment for adductor spasmodic dysphonia.

نویسندگان

  • G S Berke
  • K E Blackwell
  • B R Gerratt
  • A Verneil
  • K S Jackson
  • J A Sercarz
چکیده

During the past decade, botulinum toxin (Botox) has emerged as the accepted treatment for adductor spasmodic dysphonia (ASD). This therapy, which produces bilateral weakness of the thyroarytenoid muscle, undoubtedly produces physiologic effects that are beneficial to patients with ASD. However, it also has important limitations, including the need for repeated injections, the unpredictable relationship between dosage and response, and the possibility of short-term swallowing and voice problems. In this study, we will report our preliminary experience with a new surgical treatment for ASD. In this new procedure, the adductor branch of the recurrent laryngeal nerve is selectively denervated bilaterally, and its distal nerve stumps are reinnervated with branches of the ansa cervicalis nerve. Each of the patients was followed for at least 12 months; the median follow-up is 36 months. The outcome of the operation in 21 consecutive patients is reported. Nineteen of the 21 patients were judged to have an overall severity of dysphonia that was "absent to mild" following the procedure. Only 1 patient underwent further treatment with Botox postoperatively. The implications of this new procedure for ASD are discussed.

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Functional reinnervation of vocal folds after selective laryngeal adductor denervation-reinnervation surgery for spasmodic dysphonia.

Selective laryngeal adductor denervation-reinnervation surgery (SLAD-R) offers a viable surgical alternative for patients with adductor spasmodic dysphonia refractory to botulinum toxin injections. SLAD-R selectively denervates the symptomatic thyroarytenoid muscle by dividing the distal adductor branch of the recurrent laryngeal nerve (RLN), and preventing reinnervation, by the proximal RLN an...

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Long-term follow-up results of selective laryngeal adductor denervation-reinnervation surgery for adductor spasmodic dysphonia.

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Treatment of adductor spasmodic dysphonia with selective laryngeal adductor denervation and reinnervation surgery.

Spasmodic dysphonia (SD) is a voice disorder characterized by abnormal intermittent spasms of intralaryngeal muscles that result in voice breaks during speech. In the adductor variant of spasmodic dysphonia (ADSD), spasms of the adductor muscles cause strangled voice breaks and a strained-strangled voice quality. In the abductor variant (ABSD), spasms of the posterior cricoarytenoid muscle (PCA...

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Surgery or botulinum toxin for adductor spasmodic dysphonia: a comparative study.

OBJECTIVES Currently, botulinum toxin (Botox) injection is the standard of treatment for adductor spasmodic dysphonia (ADSD). We sought to compare the outcome of selective laryngeal adductor denervation-reinnervation (SLAD-R) surgery for ADSD to that of Botox injections. METHODS Patient-oriented measures (VHI-10) and objective single-blinded gradings of digital voice recordings were utilized ...

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Systematic Review/Meta-analysis Effect of Botulinum Toxin and Surgery among Spasmodic Dysphonia Patients: A Systematic Review

Objective. The effect of botulinum toxin among patients with adductor spasmodic dysphonia (AdSD) is temporary. To optimize long-term treatment outcome, other therapy options should be evaluated. Alternative treatment options for AdSD comprise several surgical treatments, such as thyroarytenoid myotomy, thyroplasty, selective laryngeal adductor denervationreinnervation, laryngeal nerve crush, an...

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عنوان ژورنال:
  • The Annals of otology, rhinology, and laryngology

دوره 108 3  شماره 

صفحات  -

تاریخ انتشار 1999