Viruses of Poliomyelitis
نویسندگان
چکیده
Qualitative immunological differences exist between early passage strains or so called human strains of the virus of poliomyelitis. These differences show a relationship to the epidemic source of the virus and are exemplified in this study by 4 strains isolated in different years during an eastern and western epidemic of poliomyelitis.
منابع مشابه
Interference between Poliomyelitis Viruses in Tissue Culture
The inhibition of multiplication of one poliomyelitis virus by a poliomyelitis virus of another immunologic type has been established by using tissue cultures of monkey testes. The degree of interference varied from none, to partial, to complete, depending upon the time between inoculation of the interfering and the challenge viruses, and the amount of each virus inoculated. Reciprocal interfer...
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متن کاملAn Epidemic of Paralytic Poliomyelitis Characterized by Dual Infections with Poliomyelitis and Coxsackie Viruses
The first known epidemic of poliomyelitis in Easton, Pennsylvania, occurred in 1949, and was unusual in the high proportion of paralytic to non-paralytic cases. Both poliomyelitis and Cosxackie, or C, viruses were isolated from more than half the patients studied during the acute stage of the disease. One month later C virus was only occasionally recovered. Classification of the 28 strains of C...
متن کاملModification of the Homotypic Specificity of Poliomyelitis Complement-fixing Antigens by Heat
Fluid obtained from HeLa cell cultures infected with poliomyelitis viruses served as a complement-fixing antigen. When used in the native state, i.e. untreated in any way, the fluids acted as homotypically specific antigens. When heated, however, the antigenicity was broadened and a high degree of heterotypic reactivity was encountered. Data are presented indicating that the observed group reac...
متن کاملThe Sparing Effect of Coxsackie Virus Infection on Experimental Poliomyelitis
Young mice infected with Group B Coxsackie virus were rendered markedly resistant to poliomyelitis virus given from 4 to 10 days later. A sparing effect was detectable in somewhat older mice and in young mice inoculated with poliomyelitis after shorter intervals, but in both cases few mice survived. Interference was manifest by survival, by prolongation of the course of poliomyelitis, and by a ...
متن کاملThe Coxsackie viruses.
Coxsackie is a village on the banks of the Hudson River in upper New York State. In the course of investigating an outbreak of poliomyelitis there, Dalldorf and Sickles (1948) isolated a hitherto unrecognized filterable agent from the faeces of two children with lower limb paralysis. Neutralizing antibodies for this new virus appeared in the blood of both patients during convalescence. Attempts...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 65 شماره
صفحات -
تاریخ انتشار 1937