Musculoskeletal Symptoms in Familial Mediterranan Fever

Introduction Familial Mediterranean fever (FMF) is a genetic disease characterized by painful febrile attacks of serositis and the development of amyloidosis [1]. Since the disease first described in 1945 and the gene of the disease identified in 1992, some sets of criteria were described for the diagnosis. The most famous of these are Tel Hashomer’s (Table 1) and Yalcikaya’s criteria (Table 2) [2,3]. In the Tel Hashomer’s criteria, diagnosis is based on the major and minor criteria [2]. Typical attacks are defined as recurrent (≥ 3 at the same site), febrile (38 C or more, rectal) and short (lasting12 hours3 days) attacks. Incomplete attacks are defined as painful and recurrent attacks differing from Abstract