Immunologic Properties of Mouse Thymus Cells

Immunologic Memory Cells of Bone Marrow Origin

Individual immunocompetent precursor cells of (C57BL/10 x C3H)F(1) mouse marrow generate, on transplantation, three to five times more antibody-forming cells localized in recipient spleens during secondary than during primary immune responses. The increased burst size is immunologically specific since antigens of horse and chicken erythrocytes and of Salmonella typhimurium do not cause this eff...

Cellular Morphology and Immunologic Properties of Escherichia coli Treated With Antimicrobial Antisense Peptide Nucleic Acid

  Background & Objectives: Antisense peptide nucleic acids (PNA) that target growth essential genes show potent bactericidal properties without cell lysis. We considered the possibility that whether PNA treatment influence the bacteria total nucleic acids content and apply approach to develop a new delivery system to Dendritic cells (DCs). DCs are the most potent antigen presenting cells in th...

MORPHOLOGICA L STUDY OF MOUSE (BALB/c) THYMUS A FTER HIGH A ND LOW DOSE DEXA METHA SONE TREATMENT

Dexamethasone induces thymic atrophy and thymocyte apoptosis. In the present study histological and ultrastructural changes which occur in the thymus of the mouse (BALB/c) following treatment with high (20 mg/kg) and low (8 mg/kg) doses of dexamethasone were investigated. In low dose treated mice, apoptotic cells were observed focally and localized mainly in thymic nurse cells (T.N.C.). A z...

The Immunologic Competence of Mouse Thymus Cells Measured by the Graft vs . Host Spleen

The immunologic competence of mouse thymus cells measured by the graft vs. host spleen assay.