Title : Inbreeding by environment interactions affect gene expression in Drosophila melanogaster
نویسندگان
چکیده
* Aarhus Centre for Environmental Stress Research (ACES), Department of Ecology and Genetics, University of Aarhus, 8000 Aarhus C, Denmark Department of Genetics and Biotechnology, Danish Institute of Agricultural Sciences, 8830 Tjele, Denmark Department of Genetics, Centre for Environmental Stress and Adaptation Research, University of Melbourne, 3010 Victoria, Australia ¶ Aarhus University Hospital, Molecular Diagnostic Laboratory, 8200 Aarhus N, Denmark
منابع مشابه
Inbreeding by environmental interactions affect gene expression in Drosophila melanogaster.
Genomewide gene expression patterns were investigated in inbred and noninbred Drosophila melanogaster lines under benign and stressful (high temperature) environmental conditions in a highly replicated experiment using Affymetrix gene chips. We found that both heat-shock protein and metabolism genes are strongly affected by temperature stress and that genes involved in metabolism are differenti...
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The deleterious consequences of inbreeding, especially in the form of inbreeding depression, are well known. However, little is known about how inbreeding affects genome-wide gene expression. Here, we show that inbreeding changes transcription levels for a number of genes. Gene expression profiles of Drosophila melanogaster lines inbred to F approximately = 0.67 at different rates changed relat...
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While the population genetics of inbreeding is fairly well understood, the effects of inbreeding on the physiological and biochemical levels are not. Here we have investigated the effects of inbreeding on the Drosophila melanogaster metabolome. Metabolite fingerprints in males from five outbred and five inbred lines were studied by nuclear magnetic resonance spectroscopy after exposure to benig...
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Background: In this study, the toxicity of the different xenobiotics was tested on the fruit fly Drosophila melanogaster model system. Methods: Fly larvae were raised on food supplemented with xenobioticsat different concentrations (sodium nitroprusside (0.1-1.5 mM), S-nitrosoglutathione (0.5-4 mM), and potassium ferrocyanide (1 mM)). Emergence of flies, food intake by larvae, and pupation h...
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We present a transcriptomic analysis aimed at investigating whether the changes in gene expression that occur under inbreeding generally reduce or enhance inbreeding depression. Discerning between these two alternatives can be addressed only when both changes in expression due to inbreeding and to inbreeding depression are estimated simultaneously. We used Affymetrix 2.0 arrays to study the cha...
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