Guideline on the principles of regulatory acceptance of 3Rs (replacement, reduction, refinement) testing approaches
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An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5555 Send a question via our website www.ema.europa.eu/contact © European Medicines Agency, 2016. Reproduction is authorised provided the source is acknowledged. 15 December 2016 EMA/CHMP/CVMP/JEG-3Rs/450091/2012 Committee for Medicinal Products for Human Use (CHMP) Committee for Medicinal Products for Veterinary Use (CVMP)
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