Pyrrolo-c - a Fluorescent Nucleoside Base Analogue That Codes Efficiently as C
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چکیده
PYRROLO-dCTP The fluorescence of a nucleoside base is highly dependent on the environment of the base and the measurement of its fluorescence is a powerful and sensitive tool for the analysis of DNA and RNA structure. It is especially useful for analyzing the interaction of DNA and RNA with their corresponding binding proteins. Fluorescence measurements allow real-time probing of these structural interactions. Unfortunately, the intrinsic fluorescence of the regular bases is extremely low to non-existent, so fluorescent analogues have been sought for a long time.
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تاریخ انتشار 2003