Is testing of sperm DNA fragmentation (SDF) ready for the basic work-up of male infertility?
نویسنده
چکیده
The authors have presented an informative manuscript on testing of sperm DNA fragmentation (SDF). They presented background material on the development of these tests, and their discussions were supported by 129 references from PubMed up to June 2016. In the section entitled “Evidence Synthesis”, they reported on 8 SDF tests that have been used clinically. The final section was called “Indications for SDF Testing” and it provided ten practical examples of how these tests were utilized in different cases of male infertility. The authors concluded that there is fair evidence to suggest that SDF testing should be used along with the semen analyses as part of the male infertility work-up. Although this approach seems progressive, there is literature that has addressed the pros and cons of SDF testing (1). Therefore, this “Commentary” will probe the subject of SDF testing, and offer some constructive suggestions regarding practical applications of this emerging science. So, let’s begin!
منابع مشابه
Should sperm DNA fragmentation testing be included in the male infertility work-up?
A response to the editorial 'Are we ready to incorporate sperm DNA fragmentation testing into our male infertility work-up? A plea for more robust studies' by Erma Drobnis and Martin Johnson.
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