Visualising the membrane viscosity of porcine eye lens cells using molecular rotors.
نویسندگان
چکیده
The plasma membranes of cells within the eye lens play an important role in metabolite transport within the avascular tissue of the lens, maintaining its transparency over the entire lifespan of an individual. Here we use viscosity-sensitive 'molecular rotors' to map the microscopic viscosity within these unusual cell membranes, establishing that they are characterised by an unprecedentedly high degree of lipid organisation.
منابع مشابه
Visualising the membrane viscosity of porcine eye lens cells using molecular rotors† †Electronic Supplementary Information (ESI) available: Synthetic procedures, compound characterisation and additional spectroscopic and imaging data. See DOI: 10.1039/c6sc05369f Click here for additional data file.
International Tomography Center SB R Novosibirsk, Russia. E-mail: petr.sherin@to Department of Natural Sciences, Novosib 630090, Novosibirsk, Russia Department of Chemistry, Imperial College 2AZ, UK. E-mail: [email protected] Institute of Molecular and Cellular Biology Novosibirsk, Russia Laboratoire de Biophotonique et Pharma Pharmacie, Université de Strasbourg, 74 R France † Electronic ...
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ورودعنوان ژورنال:
- Chemical science
دوره 8 5 شماره
صفحات -
تاریخ انتشار 2017