Blue naevus with pigment network-like structure on dermoscopy.
نویسندگان
چکیده
A 58-year-old Japanese man presented with a lesion on his left forearm; a black-grey macule 4 mm in diameter that had appeared in his childhood (Fig. 1a). He worked in an office and had no history of trauma at the site of the lesion. BN and basal cell carcinoma was suspected macroscopically. On dermoscopy, however, there was a pigment network-like structure consisting of randomly arranged, black-to-grey-coloured, blurred lines of irregular width. In the centre of the lesion the lines were thicker and crowded, forming a nearly diffuse pigmentation, and faded and disappeared gradually towards the periphery (Fig. 1b). Histopathologically, the lesion comprised pigmented dermal spindle cell proliferation with a low cell density, and was restricted to the superficial dermis (Fig. 2a, b). These spindle cells were stained positively for S100 protein (Fig. 3a), but not for CD68. The pigment granules in these cells were highlighted by Masson-Fontana staining (Fig. 3b) and disappeared on application of a demelanizing process (Fig. 3c). This indicated that the spindle cells were melanocytes containing melanin granules. A diagnosis of BN was made.
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ورودعنوان ژورنال:
- Acta dermato-venereologica
دوره 88 4 شماره
صفحات -
تاریخ انتشار 2008