Five New Limonoids from Peels of Satsuma Orange (Citrus reticulata).

نویسندگان

  • Takashi Kikuchi
  • Yasuaki Ueno
  • Yoshino Hamada
  • Chika Furukawa
  • Takako Fujimoto
  • Takeshi Yamada
  • Reiko Tanaka
چکیده

Five new: 21,23-dihydro-21-hydroxy-23-oxonomilin (1), 21,23-dihydro-23-methoxy-21-oxonomilin (2), 21,23-dihydro-21-hydroxy-23-oxonomilinic acid methyl ester (3), 21,23-dihydro-23-methoxy-21-oxolimonin (4), and 21,23-dihydro-21-oxolimonin (5), and seven known limonoids were isolated from peels of satsuma orange (Citrus reticulata). The isolated compounds were evaluated for their inhibitory effects on macrophage activation by an inhibitory assay of nitric oxide (NO) production. Among them, compound (2) exhibited NO inhibitory activity without cytotoxicity.

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عنوان ژورنال:
  • Molecules

دوره 22 6  شماره 

صفحات  -

تاریخ انتشار 2017