Leser - Trélat Sign in Tumor - Stage Mycosis

نویسندگان

  • UC Davis
  • Brandon Rowe
  • Alina Shevchenko
  • Gil Yosipovitch
چکیده

A 71-year-old man presented with numerous pruritic seborrheic keratoses, with an eruptive onset over the course of 3 months. At presentation, he was also found to have hypopigmented tumors diffusely scattered throughout his body that were found to be mycosis fungoides on histologic examination. A theory regarding the pathophysiology of the development of eruptive seborrheic keratoses in the presence of mycosis fungoides is briefly discussed and 10 previous case reports of the Leser-Trélat sign in the setting of mycosis fungoides are reviewed.

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منابع مشابه

[Leser-Trélat sign associated with Sézary syndrome and transitional cell carcinoma of the bladder].

Leser-Trélat sign is characterized by the sudden onset and rapid growth in number and size of multiple seborrheic keratoses, in relation to an underlying neoplasm. It is sometimes accompanied by pruritus and often associated with acanthosis nigricans. We describe a 63-year-old man diagnosed with plaque-stage mycosis fungoides who, during phototherapy, developed severe erythema and generalized s...

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Leser-Trélat Sign without Internal Malignancy

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Sign of Leser-Trélat Associated with Esophageal Squamous Cell Cancer

The sign of Leser-Trélat is a rare paraneoplastic phenomenon marked by accelerated onset of multiple seborrheic keratoses. The occurrence of the sign often points towards underlying visceral malignancies which in a majority are adenocarcinomas of the gastrointestinal tract. We report this case of a 65-year-old man who presented with sign of Leser-Trélat and was diagnosed with poorly differentia...

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Leser-Trélat sign: does it really exist?

Leser-Trélat sign is a rare cutaneous disorder that manifests with sudden emergence of seborrheic keratoses and increase in their numbers and size within weeks or months. Its concurrence with many types of malignancies, especially adenocarcinoma and lymphoma, has been reported in the literature. In this case report, a patient having Leser-Trélat sign, without any detected malignancy in spite of...

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Leser-Trélat syndrome in patients affected by six multiple metachronous primitive cancers

Leser-Trélat syndrome is characterized by the eruptive appearance of multiple seborrheic keratoses in association with underlying malignant disease. Usually, the sign of Leser-Trélat is associated with adenocarcinoma, most frequently of the colon, breast, or stomach, but also of the lung, kidney, liver, and pancreas. Herein, we present a case that we believe is the first report of the sign of L...

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تاریخ انتشار 2016