An infant with trisomy 18 and a ventricular septal defect.

نویسندگان

  • Annie Janvier
  • Felix Okah
  • Barbara Farlow
  • John D Lantos
چکیده

Decisions for critically ill infants with trisomy 18 raise thorny issues about values, futility, the burdens of treatment, cost-effectiveness, and justice. We presented the case of an infant with trisomy 18 to 2 neonatologists with experience in clinical ethics, Annie Janvier and Felix Okah, and to a parent, Barbara Farlow. They do not agree about the right thing to do.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Double trisomy 48,XXX,+18 with multiple dysmorphic features.

BACKGROUND Chromosomal abnormality is a common cause of congenital anomalies, psychiatric disorders, and mental retardation. However, the double trisomy 48,XXX,+18 is a rare chromosome abnormality. METHODS Case report and literature review. RESULTS A 7-hour-old girl presented to our unit because of poor response after birth. She presented with multiple dysmorphic features, including small f...

متن کامل

Mosaic Trisomy 18 in a Five-Month-Old Infant

Individuals with mosaic trisomy 18, only approximately 5% of all trisomy 18 cases, carry both a trisomy 18 and an euploid cell line. Their clinical findings are highly variable, from the absence of dysmorphic features to the complete trisomy 18 syndrome. A five-month-old daughter of a 38-year-old mother, with vomiting and feeding problems, was referred to our department. She was undernourished ...

متن کامل

Antenatal diagnosis of trisomy 13 with unexpected increase in alpha-feto protein.

A 24-year-old woman who had previously given birth to an infant with Down's syndrome was shown by chromosomal analysis of the liquor amnii to be carrying an infant with trisomy D. Routine examination of serum and liquor alpha-feto protein (AFP) in the antenatal period showed unexpected high levels of both, consistent with a neural tube defect. The fetus, however, did not have evidence of a neur...

متن کامل

Origin of both great vessels from the right ventricle associated with the trisomy-18 syndrome.

T HE FIRST descriptions of the trisomy-18 syndrome were in 1960 by Edwards,' Patau,2 and Smith3 and their associates. Although there was disagreement concerning which of the three pairs of chromosomes had an extra number, it now appears to be pair 18. The major malformations involve the skin, face, heart, and the central nervous, musculoskeletal, gastrointestinal, and urogenital systems. Overla...

متن کامل

Percutaneous right ventricle outflow tract stenting in a patient with trisomy 18 associated with double outlet right ventricle.

Trisomy 18, or Edwards syndrome, is the second most common chromosome anomaly after trisomy 21. Various types of congenital heart diseases are seen in the majority of trisomy 18 patients. Palliative treatment of right ventricular outflow tract (RVOT) stenosis includes options like balloon dilatation, stenting and surgery. Herein, we present a case with trisomy 18 and double outlet right ventric...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Pediatrics

دوره 127 4  شماره 

صفحات  -

تاریخ انتشار 2011