Molecular chaperones: The busy life of Hsp90
نویسندگان
چکیده
The heat shock protein Hsp90 is a molecular chaperone which assists the refolding of misfolded proteins, but also has highly selective functions in normal metabolism. These dual functions enable Hsp90 to connect environmental conditions with developmental processes and to buffer genetic changes.
منابع مشابه
Expression of hsp90 Alpha and hsp90 Beta during Xenopus laevis Embryonic Development
Background: Members of the eukaryotic Hsp90 family function as important molecular chaperones in the assembly, folding and activation of cellular signaling in development. Two hsp90 genes, hsp90 alpha and hsp90 beta, have been identified in fish and homeothermic vertebrates but not in poikilothermic vertebrates. In the present study, the expression of hsp90 alpha and hsp90 beta genes in Xenopus...
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عنوان ژورنال:
- Current Biology
دوره 9 شماره
صفحات -
تاریخ انتشار 1999