Foreign Travel and Decreased Ciprofloxacin Susceptibility in Salmonella enterica Infections
نویسندگان
چکیده
To determine antimicrobial drug resistance patterns, we characterized nontyphoidal Salmonella enterica strains isolated in Liverpool, UK, January 2003 through December 2009. Decreased susceptibility to ciprofloxacin was found in 103 (20.9%) of 492 isolates. The lower susceptibility was associated with ciprofloxacin treatment failures and with particular serovars and phage types often acquired during foreign travel.
منابع مشابه
Decreased susceptibility to ciprofloxacin in Salmonella enterica serotype typhi, United Kingdom.
In 1999, 23% of Salmonella enterica serotype Typhi isolates from patients in the United Kingdom exhibited decreased susceptibility to ciprofloxacin (MIC 0.25-1.0 mg/L); more than half were also resistant to chloramphenicol, ampicillin, and trimethoprim. Increasing numbers of treatment failures have been noted. Most infections have been in patients with a recent history of travel to India and Pa...
متن کاملDraft Genome Sequence of Salmonella enterica Serovar Typhi IMR_TP298/15, a Strain with Intermediate Susceptibility to Ciprofloxacin, Isolated from a Typhoid Outbreak
Salmonella enterica serovar Typhi with reduced susceptibility to ciprofloxacin is increasingly being reported globally. An outbreak caused by Salmonella Typhi with decreased ciprofloxacin susceptibility has not been reported before in Malaysia. We present here the annotated draft genome of a Salmonella Typhi strain involved in a typhoid outbreak.
متن کاملAntibiotic Susceptibility Pattern of Salmonella Enterica Serovar Typhi and Paratyphi a from North India: the Changing Scenario
Enteric fever prevails as a major public health problem despite the use of antimicrobials due to the emergence of drug resistance. The present study was undertaken to find out the antimicrobial susceptibility pattern of Salmonella isolates from our region. Antimicrobial susceptibility testing for six drugs chloramphenicol (30μg), amoxicillin (10μg), cotrimoxazole (1.25/23.75μg), nalidixic acid ...
متن کاملMultiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators.
Mechanisms of antibiotic resistance were examined in nalidixic acid-resistant Salmonella enterica serovar Enteritidis field isolates displaying decreased susceptibility to ciprofloxacin and in in vitro-derived ciprofloxacin-resistant mutants (104-cip and 5408-cip). All field isolates harbored a single gyrA mutation (D87Y). Deletion of acrB and complementation with wild-type gyrA increased quino...
متن کاملCiprofloxacin-Resistant Salmonella enterica Serotype Kentucky Sequence Type 198
To the Editor: Mulvey et al. (1) reported the emergence of ciprofloxacin resistance in Salmonella enterica se-rovar Kentucky of multilocus sequence type 198 (ST198) in Canada (1). Cip-rofloxacin resistance in S. enterica ser. Kentucky was reported in 2011 in patients from Europe, most of whom had traveled to Africa and the Middle East (2). Since then, S. enterica ser. Ken-tucky ST198 with addit...
متن کامل