On the Excitation of Tissue by Means of Condenser Discharges

Equations are derived for the capacity-voltage relations for stimulation of tissue by condenser discharges, using the hypothesis that the local excitatory process p grows under the influence of an applied potential V according to the equation, See PDF for Equation where K and k are constants. It is further assumed that the local excitatory process becomes adequate when it attains a value h +/- alpha V where h and alpha are constants and V is the applied potential at the particular instant that the adequate value is attained. The equations so obtained are applied to the data of several authors on several types of tissue and the agreements obtained are sufficiently good. It is shown in one case that the direct current equation and the condenser discharge equation each derived from the above bases are consistent when applied to data from the same preparation.