Use of cystatin C determination in clinical diagnostics.

نویسندگان

  • Jan Mares
  • David Stejskal
  • Jitka Vavrousková
  • Karel Urbánek
  • Roman Herzig
  • Petr Hlustík
چکیده

This paper presents a current view of the possible clinical uses of cystatin C determination. Cystatin C is an inhibitor of cysteine proteases, and relatively stable in the systemic circulation it is comparatively easily determined. Although in clinical practice it is known primarily as a relatively reliable and endogenous marker for glomerular filtration, lately cystatin C analysis has been discussed in connection with the diagnostics of a variety of diseases such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases.

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عنوان ژورنال:
  • Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia

دوره 147 2  شماره 

صفحات  -

تاریخ انتشار 2003