A Preliminary Study on Breed Differences in Susceptibility of Sheep to Mycotoxin Sporidesmin
نویسندگان
چکیده
Sporidesmin is the mycotoxin that causes facial eczema disease (FE) in New Zealand (NZ) livestock. In an artificial sporidesmin dosing test, the introduced Finnish Landrace sheep breed was found to be significantly more tolerant to FE than the introduced Texel breed. This finding enables cross-breeding strategies to improve disease tolerance. Combining published data with the current study, a tentative inference is that Finnish Landrace, Merino and East Friesian are more FE resistant than Romney, Texel and Border Leicester.
منابع مشابه
Interaction of sporidesmin, a mycotoxin from Pithomyces chartarum, with lipid bilayers.
Sporidesmin, a mycotoxin from Pithomyces chartarum is a hydrophobic molecule. It can therefore be easily incorporated in the cell membrane, where it is likely to cause changes in the bilayer organization and the properties of membrane proteins. In order to understand the redox behaviour of sporidesmin in a hydrophobic environment, we have investigated the effects of oxidized and reduced sporide...
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Facial eczema (FE) is a secondary photosensitization disease arising from liver cirrhosis caused by the mycotoxin sporidesmin. The disease affects sheep, cattle, deer and goats, and costs the New Zealand sheep industry alone an estimated NZ$63M annually. A long-term sustainable solution to this century-old FE problem is to breed for disease-resistant animals by marker-assisted selection. As a s...
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Facial eczema, a disease of sheep and, to a lesser extent, of cattle, has long been known in the North Island, New Zealand. The disease is contracted by grazing in pastures infected with the fungus Pithomyces chartarum (Commonwealth Mycological Institute Herbarium no. 74473). Synge & White (1959) isolated from cultures of this fungus a metabolic product which they named sporidesmin. Crystalline...
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