Cost Effectiveness of Paclitaxel-Eluting Stents for Patients Undergoing Percutaneous Coronary Revascularization
نویسندگان
چکیده
meet Bakhai, MD, MRCP,*† Gregg W. Stone, MD,‡ Elizabeth Mahoney, SCD,* Tara A. Lavelle, BA,* hunxue Shi, MS,* Ronna H. Berezin, MPH,* Betsy J. Lahue, MPH,§ Mary Ann Clark, MHA,§ ichael J. Lacey, MS,§ Mary E. Russell, MD,§ Stephen G. Ellis, MD, James B. Hermiller, MD,¶ avid A. Cox, MD,# David J. Cohen, MD, MSC,*** on behalf of the TAXUS-IV Investigators oston and Natick, Massachusetts; Barnet, England; New York, New York; Cleveland, Ohio; ndianapolis, Indiana; and Charlotte, North Carolina
منابع مشابه
Randomized trial of paclitaxel- and sirolimus-eluting stents in small coronary vessels.
AIMS Sirolimus- and paclitaxel-eluting stents effectively reduce restenosis in small coronary vessels. The relative efficacy of these drug-eluting stents in this high-risk subset is not known. METHODS AND RESULTS A total of 360 patients undergoing percutaneous coronary intervention for de novo lesions in native coronary vessels with a diameter of <2.80 mm received randomly paclitaxel-eluting ...
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BACKGROUND Drug-eluting stents are more effective in reducing restenosis than bare-metal stents. Less certain is the relative performance of 2 widely used drug-eluting stents-sirolimus- and paclitaxel-eluting stents-in diabetic and nondiabetic patients undergoing percutaneous coronary intervention in routine clinical practice. We therefore studied the long-term effectiveness and safety of sirol...
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Background. Individual randomized trials have suggested that everolimus-eluting stents may have improved clinical outcomes compared to paclitaxel-eluting stents, but individual trials are underpowered to examine outcomes such as mortality and very late stent thrombosis. Methods. Medline, Cochrane, and conference proceedings were searched for randomized trials comparing everolimus versus paclita...
متن کاملDifferential clinical responses to everolimus-eluting and Paclitaxel-eluting coronary stents in patients with and without diabetes mellitus.
BACKGROUND Some (but not all) prior trials have reported differential outcomes after percutaneous coronary intervention with paclitaxel-eluting stents versus stents eluting rapamycin analogs according to the presence of diabetes mellitus. These studies lacked sufficient power to examine individual safety and efficacy end points. METHODS AND RESULTS To determine whether an interaction exists b...
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BACKGROUND There is no consensus regarding the safety and efficacy of drug-eluting stents, as compared with bare-metal stents, in patients with ST-segment elevation myocardial infarction who are undergoing primary percutaneous coronary intervention (PCI). METHODS We randomly assigned, in a 3:1 ratio, 3006 patients presenting with ST-segment elevation myocardial infarction to receive paclitaxe...
متن کاملCost effectiveness of drug eluting coronary artery stenting in a UK setting: cost-utility study.
OBJECTIVE To assess the cost effectiveness of drug eluting stents (DES) compared with conventional stents for treatment of symptomatic coronary artery disease in the UK. DESIGN Cost-utility analysis of audit based patient subgroups by means of a simple economic model. SETTING Tertiary care. PARTICIPANTS 12 month audit data for 2884 patients receiving percutaneous coronary intervention wit...
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