Bovine Leukosis Virus Update II: Impact on Immunity and Disease Resistance
نویسنده
چکیده
Introduction Bovine Leukosis Virus (BLV) is a retroviral infection that causes leukemia in cattle by targeting white blood cells and causing them to grow uncontrollably. Most BLV-infected cattle seldom present with outward clinical signs. Approximately 30% of infected animals, however, will have abnormally high white blood cell counts and up to 5% will develop malignant tumors or lymphosarcomas. The most severe cases of BLV will exhibit enlarged lymph nodes, weight loss, loss of appetite, infertility and decreased milk production [1, 2]. The virus is transferred from cow to cow by BLV-laden white blood cells found in blood, saliva, semen and milk.
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