Thalamic Mediation of Hypoxic Respiratory
نویسندگان
چکیده
1 DEPRESSION IN LAMBS 2 3 4 Brian J. Koos1, Arezoo Rajaee1, Basil Ibe3, Catalina Guerra, and Lawrence Kruger2 5 6 Departments of Obstetrics & Gynecology and Neurobiology, David Geffen School of 7 Medicine at UCLA, Los Angeles, CA 90095; and Department of Pediatrics, and 8 3, C. W. Steers Biological Resource Center, Los Angeles Biomedical Research 9 Institute, Harbor-UCLA Medical Center, Torrance, CA 90502 10 11 12 Running Head: Thalamic role in hypoxic respiratory depression 13 14 Correspondence: Brian J. Koos, M.D., D.Phil. 15 David Geffen School of Medicine at UCLA 16 Dept Obstetrics and Gynecology 17 10833 Le Conte Avenue 18 Los Angeles, CA 90095-1740 19 Email: [email protected] 20 Telephone Number: 310-502-7848 21 22 23 24 Articles in PresS. Am J Physiol Regul Integr Comp Physiol (January 27, 2016). doi:10.1152/ajpregu.00412.2015
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Thalamic mediation of hypoxic respiratory depression in lambs.
Immaturity of respiratory controllers in preterm infants dispose to recurrent apnea and oxygen deprivation. Accompanying reductions in brain oxygen tensions evoke respiratory depression, potentially exacerbating hypoxemia. Central respiratory depression during moderate hypoxia is revealed in the ventilatory decline following initial augmentation. This study determined whether the thalamic paraf...
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