Repeated Acute Stress Alters Activity of Serum Aminotransferases and Lactate Dehydrogenase in Rat
نویسندگان
چکیده
Serum glutamate oxaloacetate transaminase (SGOT), glutamate pyruvate transaminase (SGPT) and lactate dehydrogenase (LDH) activities increased significantly in rats restrained (RS) for 1 hour and exposed to force swimming exercise (FS) for 15min after an interval of 4 h thereby indicating tissue damage due to stress. The results further reveal that after initial stress exposure rats do respond to a second stressor either with increased intensity (SGPT activity) or at the level similar to first exposure (LDH & SGOT activity).(JPBS 2010;Volume 23 No.2:1-4)
منابع مشابه
VARIATIONS BY EPINEPHRINE OF HEPATIC AND SERUM AMINOTRANSFERASES AND LACTATE DEHYDROGENASE IN THE RAT
Incubation of rat hepatocytes with epinephrine inhibited alanine aminotransferase (ALT) (80%) and aspartate aminotransferase (AST) (53%) activities with no effect on lactate dehydrogenase (LDH) activity. Injection of epinephrine caused a progressive increase with time in hepatic LDH activity, being 52% at 24 h. Preinjection with propranolol eliminated the hormone effect and caused further ...
متن کاملInvestigating the role of acute and repeated stress on remote ischemic preconditioning-induced cardioprotection
Objective(s): To study the effect of acute and repeated stress on cardioprotection-induced by remote ischemic preconditioning (RIPC).Materials and Methods: RIPC was induced by giving 4 short cycles of ischemia and reperfusion, each consisting of five min. The Langendorff’s apparatus was used to perfuse the isolated rat hearts by subjecti...
متن کاملHepatotoxicity and Ultra Structural Changes in Wistar Rats treated with Al2O3 Nanomaterials.
The present study was designed to evaluate the hepatotoxicity of aluminium oxide (Al2O3). To achieve this objective, Al2O3 of three different sizes (30nm, 40nm and bulk) was orally administered for 28 days to 9 groups of 10 Wistar rats each, at the dose of 500, 1000 and 2000 mg/Kg/rat. A tenth group of 10 rats received distilled water and served as control. After 28 days of exposure, the animal...
متن کاملEffect of wood betony (Stachys lavandulifolia Vahl) extract on some serum biochemical changes and acute stress response in juvenile common carp (Cyprinus carpio)
The effects of four different levels of wood betony (WB) (Stachys lavandulifolia Vahl) extract (0, 2, 4 and 8% W/W in the diet) were investigated on some serum enzymatic activities and acute stress response of juvenile common carp (Cyprinus carpio). After 10 weeks post feeding, two groups of fish (0 and 8% WB) were subjected to handling and crowding stress and the stress responses including ser...
متن کاملDietary thyme essential oil (Thymus vulgaris) changes serum stress markers, enzyme activity, and hematological parameters in gibel carp (Carassius auratus gibelio) exposed to silver nanoparticles
Gibel carp (Carassius auratus gibelio) juveniles with an average weight of 8.73± 2.1 g were fed a basal diet (control) and three experimental diets (T200, T400 and T800), containing 200, 400 and 800 mgkg-1, respectively of thyme essential oil (Thymus vulgaris) for six weeks. After six weeks feeding trial, both control and thyme essential oil-added feed groups were exposed to sub-acute toxicity ...
متن کامل