147 - Antidepressants and Antipsychotics

نویسندگان

  • Michael R. Christian
  • Sean M. Bryant
چکیده

MONOAMINE OXIDASE INHIBITORS Phenelzine (Nardil) and tranylcypromine (Parnate) are the two most commonly prescribed MAOIs in the United States, and they account for the majority of toxicity seen with this class of agents. The pharmacologic effects of MAOIs are listed in Box 147.1. These effects in overdose may result in a sympathomimetic toxidrome followed by profound hypotension. A therapeutic dose of an MAOI can interact with certain foods, drinks, and other pharmacologic agents and cause serious toxicity.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Combined treatment with atypical antipsychotics and antidepressants in treatment-resistant depression: preclinical and clinical efficacy.

Several clinical reports have documented a beneficial effect of adding atypical antipsychotic drugs to ongoing treatments with antidepressants, particularly selective serotonin reuptake inhibitors, in ameliorating drug-resistant depression. The aim of this paper was to summarize some preclinical evidence describing the mechanism responsible for the therapeutic action of combined treatment with ...

متن کامل

Atypical antipsychotic drugs and diabetes mellitus in a large outpatient population: a retrospective cohort study.

PURPOSE Previous research has suggested an association between use of atypical antipsychotics and onset of diabetes mellitus. We sought to compare the incidence of new onset diabetes among patients receiving atypical antipsychotics, traditional antipsychotics or antidepressants. METHODS Retrospective cohort study of outpatients with claims for atypical antipsychotics (n = 10 265) compared to ...

متن کامل

Risk of death and hospital admission for major medical events after initiation of psychotropic medications in older adults admitted to nursing homes.

BACKGROUND Despite safety-related concerns, psychotropic medications are frequently prescribed to manage behavioural symptoms in older adults, particularly those with dementia. We assessed the comparative safety of different classes of psychotropic medications used in nursing home residents. METHODS We identified a cohort of patients who were aged 65 years or older and had initiated treatment...

متن کامل

Nationwide time trends in dispensed prescriptions of psychotropic medication for children and adolescents in Denmark.

OBJECTIVE The analysis of time trends in dispensed prescriptions of psychotropic medications for children and adolescents in Denmark. METHOD The entire data set of the Danish prescription register covering stimulants, antidepressants, antipsychotics, and anxiolytics used in children and adolescents over a 15-year time span from 1996 to 2010 was analyzed. Both non-adjusted age-standardized pre...

متن کامل

Use of antipsychotic and antidepressant within the Psychiatric Disease Centre, Regional Health Service of Ferrara

BACKGROUND This study aimed at describing the type and dosage of psychopharmaceuticals dispensed to patients with psychiatric disorders and to assess the percentage of patients treated with antipsychotics and antidepressants, the associated therapies, treatment adherence, and dosages used in individuals registered at the Psychiatric Disease Center (PDC), Regional Health Service of Ferrara. ME...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013