Running Head: Regulation of NMDAR activation in RGCs
نویسندگان
چکیده
Disinhibitory Recruitment of NMDA Receptor Pathways in Retina 1 2 Running Head: Regulation of NMDAR activation in RGCs 3 Authors: Santhosh Sethuramanujam, Malcolm M. Slaughter. 4 Center for Neuroscience and Department of Physiology and Biophysics 5 University at Buffalo, Buffalo, NY-14214 USA 6 Corresponding Author: 7 Santhosh Sethuramanujam. 8 Department of Physiology and Biophysics, 9 124 Sherman Hall, 3435 Main Street, 10 Buffalo, NY 14214 USA. 11 [email protected] 12 TEL: 7168293240 FAX: 7168292344 13 14 NEUROSCIENCE: CELLULAR/MOLECULAR 15 16 Pages: 27 Figures: 7 Total words: 5779 17 18
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Developmental plasticity of NMDA receptor function in the retina and the influence of light.
Despite the early expression of NMDA receptors (NMDARs) in the retina, not much is known about their regulation and involvement in plasticity processes during retinal development and synapse formation. Here we report that NMDAR function in the inner retina is developmentally regulated and controlled by ambient light condition. A prominent down-regulation after eye opening of NMDAR function was ...
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